Abstract
Heavy metal exposure, such as lead (Pb), poses a severe threat to human health due to its toxic nature, which can trigger vital organ damage, particularly in the kidneys. The 'silver human' group is at high risk of Pb exposure due to the routine application of metallic paint over their entire bodies. This research aimed to evaluate the correlation between blood lead concentrations and serum creatinine levels as an indicator of kidney function among silver humans in Kediri City. This observational study, utilizing a cross-sectional design, involved six silver human subjects selected through total sampling. Pb analysis was performed using Atomic Absorption Spectrophotometry (AAS), while creatinine levels were assessed using standard laboratory methods. All respondents (100%) exhibited Pb levels within the normal range, with an average of 7.000 µg/dL. However, regarding the creatinine parameter, 50% of the respondents were found to have levels exceeding the normal threshold. Pearson statistical analysis indicated a p-value of 0.785 (p > 0.05). Consequently, no significant correlation was observed between blood lead levels and creatinine concentrations among the research subjects in Kediri City.
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Flora, G., Gupta, D., & Tiwari, A. (2012). Toxicity of lead: A review with recent updates. Interdisciplinary Toxicology, (5th ed.).
Haryadi. (2019). Hubungan Kadar Timbal Darah dan Kreatinin Darah pada Masyarakat Sekitar Terminal Bus di Yogyakarta. Jurnal Kesehatan Lingkungan Indonesia, 4(2), 112–119.
Jarup, L. (2003). Hazards of heavy metal contamination. British Medical Bulletin.
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Kurniawan, R. A., & Pratiwi, A. D. (2021). Analisis Paparan Logam Berat pada Pekerja Sektor Informal: Tinjauan Kesehatan Kerja. Jurnal Keselamatan Dan Kesehatan Kerja, 8(2), 112–120.
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Salazar-Flores, J., D. (2018). Lead Exposure and Its Relationship with Oxidative Stress and Kidney Function in Occupational Workers. Journal of Toxicological Sciences, 4(2), 121–129.
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(ATSDR)., A. for T. S. and D. R. (2020). Toxicological Profile for Lead. U.S. Department of Health and Human Services.
Borgese, L., D. (2021). Lead exposure in artistic activities: A review of the risks and preventive measures. Journal of Occupational and Environmental Hygiene, 18(4), 167–182.
Flora, G., Gupta, D., & Tiwari, A. (2012). Toxicity of lead: A review with recent updates. Interdisciplinary Toxicology, (5th ed.).
Haryadi. (2019). Hubungan Kadar Timbal Darah dan Kreatinin Darah pada Masyarakat Sekitar Terminal Bus di Yogyakarta. Jurnal Kesehatan Lingkungan Indonesia, 4(2), 112–119.
Jarup, L. (2003). Hazards of heavy metal contamination. British Medical Bulletin.
Kathuria, P. (2023). Lead Nephropathy: Pathophysiology and Clinical Manifestations. Medscape Reference.
Kurniawan, R. A., & Pratiwi, A. D. (2021). Analisis Paparan Logam Berat pada Pekerja Sektor Informal: Tinjauan Kesehatan Kerja. Jurnal Keselamatan Dan Kesehatan Kerja, 8(2), 112–120.
Pizzorno, J. (2014). The toxicity of lead: A review. Integrative Medicine. A Clinician’s Journal, 13(4), 8–12.
Salazar-Flores, J., D. (2018). Lead Exposure and Its Relationship with Oxidative Stress and Kidney Function in Occupational Workers. Journal of Toxicological Sciences, 4(2), 121–129.
Sugiani, P. P., D. (2023). Analisis Kadar Timbal dalam Spesimen Darah Pekerja Bengkel Motor di Wilayah Badung. Jurnal Laboratorium Medis, 4(1), 114–121.
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