Abstract
Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by a steadily increasing prevalence both globally and nationally. Patients with DM are highly susceptible to various infections, with Urinary Tract Infection (UTI) being one of the most frequent complications. The hyperglycemic state in DM patients leads to glycosuria, a condition where the presence of glucose in the urine creates an ideal environment for the proliferation of pathogenic microorganisms. Microbiologically, Gram-negative bacteria are the primary etiology of UTIs in diabetic patients. Bacteria such as Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis possess specific virulence factors that facilitate adherence to the urinary tract epithelium. The objective of this research was to identify Gram-negative bacteria and determine their percentage distribution among Diabetes Mellitus patients at Public Health Center X in Kediri. This research employed a descriptive research method with an accidental sampling technique, utilizing 14 urine specimens from DM patients. The results revealed the presence of Klebsiella sp. (36%), Escherichia coli (50%), and Salmonella sp. (14%) in the urine of the subjects. Based on these findings, it can be concluded that urinary tract infections in Diabetes Mellitus patients at Public Health Center X, Kediri, are caused by several types of pathogenic bacteria, with the highest prevalence being Escherichia coli, followed by Klebsiella sp., Salmonella sp., and Proteus sp. Early detection and management of bacterial infections are essential to prevent further complications in patients with Diabetes Mellitus
References
Cahyawaty,W, U., & M, M. (2022). Gambaran leukositturia tanda infeksi saluran kemih pada penderita diabetes melitus tipe-2 di RSUD kota Pontianak.JurnalBiotekMedisianaIndonesia,1119,doi:https://dx.doi.org/10.22435/jbmi.v11i1.6076
Dinkes Jatim. (2022). Profil Kesehatan Provinsi Jawa Timur 2022 (2023rd ed.). DinKes Jawa Timur.
Fauziah, N., Setyowati, H., & Wijayanti, A. (2021). Karakteristik Mikrobiologi Infeksi Saluran Kemih pada Pasien Diabetes Melitus Tipe 2. Jurnal Mikrobiologi Klinik Indonesia, 9(2), 45-52.
Hidayat, R., & Utami, P. B. (2020). Analisis Hubungan Kadar Glukosa Darah dengan Bakteriuria pada Pasien Diabetes Melitus di Fasilitas Kesehatan Tingkat Pertama. Jurnal Kesehatan Kediri, 5(1), 12-19.
Hidayat, R., & Lestari, W. (2023). Analisis Mikrobiologi Urine pada Pasien Diabetes Mellitus Tipe 2 dengan Komplikasi Neuropati. Jurnal Patologi Klinik Indonesia, 15(2), 110-118.
International Diabetes Federation (IDF). IDF international atlas ninth edition (online); 2019 Diunduh dari URL : IDF Diabetes Atlas 9 th edition 2019 IDF. (2021). IDF Diabetes Atlas-10th Edition.
Pratami, A. S., dkk. (2022). Hubungan Kadar Glukosa Urine dengan Kejadian Bakteriuria pada Penderita Diabetes Mellitus. Jurnal Laboratorium Medis, 4(1), 45-52.
Pratama, A., & Wijaya, I. (2023). Pola Mikroorganisme dan Sensitivitas Antibiotik pada Infeksi Saluran Kemih Pasien Diabetes Mellitus. Jurnal Kedokteran dan Kesehatan, 19(1), 22-34.
Putra, A., dkk. (2022). Karakteristik Infeksi Saluran Kemih pada Pasien Diabetes Melitus Tipe 2: Sebuah Tinjauan Klinis. Jurnal Kedokteran dan Kesehatan Indonesia.
Putri, A. E., & Syahputra, R. (2022). Mekanisme Patogenesis Infeksi Saluran Kemih pada Kondisi Hiperglikemia. Review Jurnal Kedokteran Metabolik, 4(3), 101-110.
Ramadhani, F. S., & Sari, D. P. (2023). Profil Resistensi Bakteri Gram Negatif yang Diisolasi dari Urine Pasien Rawat Jalan. Jurnal Laboratorium Medis, 11(1), 33-40.
Sari, M., & Ramadhani, F. (2021). Karakteristik Bakteri Escherichia coli pada Urinalisis Pasien Rawat Inap Diabetes Mellitus. Journal of Health Science and Prevention, 5(3), 201-209.
Sari, I. P., & Ramadhani, F. (2022). Karakteristik Bakteriuria Asimtomatik pada Penderita Diabetes Mellitus: Sebuah Tinjauan Klinis. Jurnal Biomedika dan Kesehatan.
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